Polyethylene Glycol 400

　　Main Application Areas

　　Pharmaceutical Field (Core Application):

　　Pharmaceutical Solvent/Co-solvent: As a solvent or co-solvent for oral liquids, syrups, and injections, it can significantly improve the solubility of fat-soluble drugs (such as steroid hormones, vitamins, antibiotics) and enhance drug stability (e.g., reducing oxidation and hydrolysis). For example, injections of some poorly soluble drugs require PEG 400 as the solvent (such as certain antineoplastic drugs and analgesics).

　　Preparation Base: Used as a base or thickener in ointments, creams, and suppositories to regulate the viscosity and spreadability of the preparation (due to its liquid characteristics, it is often compounded with high molecular weight PEG to balance hardness and fluidity).

　　Transdermal Absorption Enhancer: Assists drugs in penetrating the skin barrier, improving the bioavailability of topical administration.

　　Daily Chemicals and Cosmetics:

　　Used as a humectant, solvent, or conditioner, added to skincare products (such as serums, lotions), shampoos, and body washes:

　　Can dissolve fragrances and active ingredients (such as Vitamin C derivatives, plant extracts), preventing ingredient precipitation;

　　Enhances skin hydration, and due to its small molecular size, it has moderate permeability and is gentle and non-irritating (suitable for sensitive skin).

　　Industrial Field:

　　Used as a plasticizer or leveling agent in coatings and inks to improve film formation and uniformity;

　　Used as a softener and antistatic agent in the textile industry to improve fabric hand feel;

　　Used as a lubricant in metalworking to reduce friction and wear.

　　Food Field:

　　PEG 400 that meets food-grade standards can be used as a defoamer and lubricant in food processing (such as candies, baked goods), but the usage amount must strictly comply with regulations.